Conference Info > Scientific Program

Sunday, September 23, 2018

Time Event  
14:00 - 17:30 Registration - Registration  
16:30 - 17:30 Welcome cocktail  
17:30 - 18:00 Congress opening - Philippe Giegé and Laurence Drouard, Catherine Florentz (University of Strasbourg), Francesco Bonomi (IUBMB), Nicolas Matt (City of Strasbourg, IMCBio)  
18:00 - 18:30 Keynote Lecture 1 - tRNA semiotics, fragmented ciphers and modern palimpsests - Juan Alfonzo
 
18:30 - 19:00 Keynote Lecture 2 - A Cytoplasmic tRNA Synthetase Splice Variant Promotes Mitochondrial Homeostasis - Paul Schimmel
 
19:00 - 21:30 Diner  

Monday, September 24, 2018

Time Event  
09:00 - 10:35 tRNA biogenesis in evolution - Juan Alfonzo and Mario Mörl  
09:00 - 09:25 › tRNA Travels Within Eukaryotic Cells - Anita Hopper  
09:25 - 09:50 › tRNA decay quality control pathways in yeast - Eric Phizicky  
09:50 - 10:05 › tRNA biogenesis pathway in human cells - Yasutoshi Akiyama  
10:05 - 10:20 › Processing of armless mitochondrial tRNAs in Romanomermis culicivorax – How CCA-adding enzymes recognize unusual tRNA structures - Oliver Hennig  
10:20 - 10:35 › Hierarchical groove discrimination by Class I and II aminoacyl-tRNA synthetases reveals a palimpsest of the operational RNA code in the tRNA acceptor-stem bases - Charles Carter  
10:40 - 11:00 Coffee break  
11:00 - 12:30 tRNA biogenesis in evolution - Sidney Altman endowment session  
11:00 - 11:30 › tRNAs and proteins use the same import channel for translocation across the mitochondrial outer membrane of trypanosomes - André Schneider  
11:30 - 12:00 › Structural basis of tRNA aminoacylation-dependent transcription attenuation by a T-box riboswitch - Jinwei Zhang  
12:00 - 12:15 › Studies on bacteria that encode two types of RNase P, the classical RNA-based and a novel RNA-free RNase P - Roland K. Hartmann  
12:15 - 12:30 › Roles and interplay of the subunits of human mitochondrial RNase P - Walter Rossmanith  
12:30 - 12:40 Three flash talks - Shikha Shikha - Eleni Kaliatsi - Isabell Schencking  
12:40 - 14:00 Lunch  
14:00 - 15:50 tRNA modifications - Henri Grosjean and Valérie de Crécy-Lagard  
14:00 - 14:25 › Comparative genomic analysis of queuine salvage in bacteria leads to the discovery of novel enzymes - Valerie de Crecy-Lagard  
14:25 - 14:50 › tRNA modifications and cellular quality control - Sebastian Leidel  
14:50 - 15:05 › The noncanonical lysine acetyltransferase activity of Elongator complex subunit 3 - Ting-Yu Lin  
15:05 - 15:20 › t6A modification of A37 position in tRNA and its role in plant development - Elena Zemlyanskaya  
15:20 - 15:35 › Structure of yeast tRNA Nm34 methyltransferase Trm7-Trm734 complex reveals its novel bipartite interaction essential for 2´-O-methylation of N34 in the wobble position of three specific tRNA species - Akira Hirata  
15:35 - 15:50 › Structural characterisation of bacterial m1A22 tRNA methyltransferase TrmK: Insights into tRNA recognition - Carine Tisné  
15:50 - 16:00 Three flash talks - Rościsław Krutyhołowa - Francesca Tuorto - Laura Antoine  
16:00 - 16:30 Coffee break  
16:30 - 18:20 tRNA modifications - Henri Grosjean and Valérie de Crécy-Lagard  
16:30 - 16:55 › Dynamic regulation of tRNA modification under physiological and pathological conditions - Tsutomu Suzuki  
16:55 - 17:20 › Diversity of I34 tRNAs in extant species, and their impact on proteome composition - Lluís Ribas de Pouplana  
17:20 - 17:35 › Structure and Mechanism of Threonylcarbamoyl Adenosine Biosynthesis in Bacteria - Naduni Paranagama - Manal Swairjo  
17:35 - 17:50 › CRYSTAL STRUCTURES OF [4Fe-4S]-DEPENDENT tRNA THIOLASES REVEAL A NEW MECHANISM OF tRNA THIOLATION - Béatrice Golinelli-Pimpaneau  
17:50 - 18:05 › TrmA plays an important role during early tRNA maturation by methylating and folding all tRNAs - Ute Kothe  
18:05 - 18:20 › Structural and biochemical analysis of the dual-specificity Trm10 enzyme from Thermococcus kodakaraensis prompts reconsideration of its catalytic mechanism. - Ranjan Kumar Singh  
18:20 - 18:35 Four flash talks - Eva Hegedüsová - Sophia Missoury - Mari Tagel - Qinghai Zhang  
19:00 - 20:30 Diner  
20:30 - 21:30 Poster session 1
 

Tuesday, September 25, 2018

Time Event  
09:00 - 10:40 tRNA in translation - Yaser Hashem and Joseph Puglisi  
09:00 - 09:25 › Dynamic role of tRNA in biology - Joseph Puglisi  
09:25 - 09:50 › Protein synthesis: from ribosome assembly to targeting of membrane proteins - Nenad Ban  
09:50 - 10:05 › Logical engineering of D-arm and T-stem of tRNA for incorporation of non-proteinogenic amino acids - Takayuki Katoh  
10:05 - 10:20 › Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 and E-tRNA - Bertrand Beckert  
10:20 - 10:35 › Unique composition and architecture of Arabidopsis thaliana mitochondrial ribosome - Florent Waltz  
10:35 - 10:40 Two flash talks - Sylvain Debard - Jessica Hobson  
10:40 - 11:00 Coffee break  
11:00 - 12:40 tRNA in translation - Yaser Hashem and Joseph Puglisi  
11:00 - 11:25 › Human mitoribosomes: their idiosyncrasies and behaviour - Zofia Chrzanowska-Lightowlers  
11:25 - 11:50 › A cellular Quisling factor: antibacterial RNase toxins collaborate with elongation factor Tu to cleave specific tRNA isoacceptors - Christopher Hayes  
11:50 - 12:05 › tRNA accommodation during archaeal translation initiation - Yves Mechulam  
12:05 - 12:20 › Concerted regulation of mitochondrial and nuclear tRNA processing - Aleksandra Filipovska  
12:20 - 11:35 › Cellular levels of readthrough inducing tRNAs and their consequences in yeast and mammals. - Petra Beznoskova  
12:35 - 12:40 Two flash talks - Lorenzo Leiva - Mariia Rybak  
12:40 - 14:00 Lunch  
14:00 - 14:55 tRNA in translation - Yaser Hashem and Joseph Puglisi  
14:00 - 14:25 › Polymorphic mutations linked to tRNA and changes of local speed of mRNA translation - Zoya Ignatova  
14:25 - 14:40 › tRNA-recognition mechanism of Sec-synthetic enzymes - Miljan Simonovic  
14:40 - 14:55 › Reading the ribosome: monitoring translation in living cells with FRET-labeled tRNAs - Wissam Mansour  
15:00 - 16:20 tRNAomics and synthetic biology - Shigeyuki Yokoyama and Eric Westhof  
15:00 - 15:25 › Non-coding RNA-guided genome editing by CRISPR-Cas - Osamu Nureki  
15:25 - 15:50 › Natural non-canonical amino acids and the genetic code - Dieter Söll  
15:50 - 16:05 › pyRNAms enables semi-automated high-throughput nucleoside mass spectrometry data analysis for the common user - Johannes Leufken  
16:05 - 16:20 › RNA-seq for absolute quantification: Reprogramming the tRNA landscape during stress-induced bacterial persistence - Jennifer Hu  
16:20 - 16:40 Coffee break  
16:40 - 17:40 tRNAomics and synthetic biology - Shigeyuki Yokoyama and Eric Westhof  
16:40 - 17:05 › Massively Parallel Human Systems Biology in Synthetic Organisms - Jesse Rinehart  
17:05 - 17:20 › Characterization of changes in codons usage and tRNA expression levels during T-cells activation. - Roni Rak  
17:20 - 17:35 › Re-coding the Saccharomyces cerevisiae genome through codon ambiguities - Ana Rita Guimarães  
17:35 - 17:40 Two flash talks - Noa Aharon-Hefetz - Damien Jeandard  
17:45 - 19:00 Functions of tRNA fragments and non canonical functions of tRNA - Anita Hopper and Magali Frugier  
17:45 - 18:10 › Mechanisms of translation inhibition by tRNA-derived stress-induced RNAs - Pavel Ivanov  
18:10 - 18:35 › Elucidating the function of 3ʹtsRNAs in post transcriptional -mediated gene regulation in mammals - Mark Kay  
18:35 - 18:50 › The multifaceted roles of ribosome-associated tRNA-derived fragments during translation control - Norbert Polacek  
19:00 - 20:30 Diner  
20:30 - 21:30 Poster session 2
 

Wednesday, September 26, 2018

Time Event  
09:00 - 09:55 Functions of tRNA fragments and non canonical functions of tRNA - Anita Hopper and Magali Frugier  
09:00 - 09:25 › Lost in translation? Transfer RNAs and graft-mobile mRNAs - Friedrich Kragler  
09:25 - 09:40 › Expression of tRNAs clustered nuclear genes in Arabidopsis thaliana - Guillaume Hummel  
09:40 - 09:55 › Enhanced tRNA gene transcription by RNA polymerase III activated in response to DNA virus infection - Nayef Jarrous  
09:55 - 10:10 Conference picture  
10:10 - 10:30 Coffee break  
10:30 - 11:30 Functions of tRNA fragments and non canonical functions of tRNA - Anita Hopper and Magali Frugier  
10:30 - 10:55 › Cracking the Code of Regulated Human tRNA Genes - Todd Lowe  
10:55 - 11:10 › Drosophila tsRNAs preferentially suppress general translation machinery via antisense pairing and participate in cellular starvation response - Jian Lu  
11:10 - 11:25 Four Flash talks - Cristina Cosentino - Y Gonskikh - Anna Mleczko- Mathieu Bruggeman  
11:30 - 12:30 Lunch box  
12:20 - 13:30 Bus - Departure  
14:00 - 17:00 Visit - Haut-Koenigsbourg castle  
16:00 - 17:00 Bus - Departure  
16:30 - 17:30 Dopff-Moulin - Visit of the vineyard and wine tasting  
17:30 - 19:00 Visit - The village Riquewihr  
19:30 - 21:30 "Tarte flambée" diner at Dopff-Moulin Alsatian folk music  
22:00 - 22:00 Bus - Departure  

Thursday, September 27, 2018

Time Event  
09:00 - 10:40 Amino acyl tRNA synthetases - Hubert Becker and Claude Sauter  
09:00 - 09:25 › Aminoacyl-tRNA synthetases in Charcot-Marie-Tooth disease: Mechanistic Insights and Therapeutic Opportunities - Xiang-Lei Yang  
09:25 - 09:50 › Glu-Pro tRNA synthetase is a constituent of a post-translational metabolon regulating adipocyte lipid metabolism - Paul Fox  
09:50 - 10:05 › Adaptive Partitioning of the tRNA Interaction Interface by Aminoacyl-tRNA Synthetases - David Ardell  
10:05 - 10:20 › Mammalian Cell Migration and Socialization is Induced by exogenous tRNA - Susan Martinis  
10:20 - 10:35 › Reversible inactivation of yeast mitochondrial phenylalanyl-tRNA synthetase under oxidative stress - Rajat Banerjee  
10:40 - 11:00 Coffee break  
11:00 - 12:40 Amino acyl tRNA synthetases - Hubert Becker and Claude Sauter  
11:00 - 11:25 › Making Drugs from tRNA Synthetases - Sunghoon Kim  
11:25 - 11:40 › Lysyl-tRNA synthetase produce second messenger Ap4A to propagates signals by polymerizing target protein - Jing Wang  
11:40 - 11:55 › Characterizaton of MprF-like lipid aminoacylation factors in fungi - Nathaniel Yakobov  
11:55 - 12:10 › A New Metalloprotein That Promotes Indirect tRNA Aminoacylation - Whitney Wood  
12:10 - 12:25 › Mitochondrial localized glycyl-tRNA synthetase OsGlyRS2 participates in plant response to ambient temperature - Qiang Hao  
12:25 - 12:30 Two Flash talks - Maxwell Baymiller - Marta Ferreira Amaral  
12:40 - 14:00 Lunch  
14:00 - 16:00 tRNA biology and diseases - Marie Sissler and Ivan Tarassov  
14:00 - 14:25 › Expression of an arginine tRNA modulates neuronal excitability - Susan Ackerman  
14:25 - 14:50 › Lack of Trit1-mediated tRNA isopentenylation impacts on cytoplasmic and mitochondrial translation and leads to mitochondriopathy and seizures - Ulrich Schweizer  
14:50 - 15:05 › Structural of the translation preinitiation complex from the pathogenic protozoa Trypanosoma cruzi - Yaser Hashem  
15:05 - 15:20 › tRNA methylation A Determinant of Mitochondrial Pathogenesis - Ya-Ming Hou  
15:20 - 15:35 › A deafness-associated mitochondrial DNA mutation perturbed the tertiary interaction and function of tRNASer(UCN) - Min-Xin Guan  
15:35 - 15:50 › TRMT1-catalyzed tRNA modifications ensure proper proteostasis and neurodevelopment - Dragony Fu  
16:00 - 16:30 Coffee break  
16:30 - 17:30 tRNA biology and diseases - Marie Sissler and Ivan Tarassov  
16:30 - 16:55 › “Unboxing” the diversity of tRNA-mediated transcription regulation in pathogens - Constantinos Stathopoulos  
16:55 - 17:10 › A model for dealing with codon mismatches in host-virus interactions: Hijacking the human tRNA epitranscriptome during flavivirus infection - Cheryl Chan  
17:10 - 17:25 › Phosphorylated Lysyl-tRNA synthetase (LysRS) as biomarker for cancer and cardiac prognosis - Saravanan Vivekanandan  
17:25 - 17:30 Two Flash talks - Yu Nagayoshi - Ana Raquel Soares  
17:30 - 18:00 Poster - Prizes awards  
18:00 - 18:45 Keynote lecture 3 - Elongation factor P is required to maintain proteome homeostasis at high growth rate - Mike Ibba
 
18:45 - 19:00 Closing remarks  
19:30 - 22:00 Gala diner  
  
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